The Frederick Knecht Detwiller collection consists of paintings, prints, watercolors, ephemera, and archives.

Detwiller (1882–1953), a 1904 graduate of Lafayette College, was a painter of rural and urban landscapes. After graduation, he received a law degree and studied architecture. While studying architecture in Paris, he decided to become a painter. He returned to New York, established a fall/winter studio at Carnegie Studios in New York City, and a summer studio in New Harbor, Maine. He was artist-in-residence at Lafayette from 1948 until his death in 1953. The art collection also includes original copper plates for several of his etchings. The archival portion of the Detwiller collection is housed in Skillman Library’s Rare Books and Special Collections.